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Recent insights into omega-3 fatty acid regulation of adipose tissue metabolism


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Carla Taylor, Mandana Pahlavani



Carla Taylor, PhD - University of Manitoba
Mandana Pahlavani, PhD -Texas Women's University


Omega-3 polyunsaturated fatty acids (N3-PUFA) are widely recognized for their roles in reducing disease risks and promoting cardiometabolic health. Adipose tissues are one of the major sites in which N3-PUFA exert their beneficial effects by modulating signalling pathways, adipokine production, inflammation, and energy expenditure. The objective of this webinar is to provide attendees with recent insights regarding the roles of different N3-PUFA in brown and white adipose tissues, and how these important fatty acids can improve cardiometabolic health.


  1. Highlight new knowledge regarding N3-PUFA regulation of brown and white adipose tissue functions
  2. Demonstrate that N3-PUFA can improve cardiometabolic risks through the modulation of lipid handling, adipokine production, and energy expenditure, amongst other pathways.
  3. Provide updates of the shared and distinct roles of different N3-PUFA in adipose tissues

Moderator: David Mutch, PhD - University of Guelph

About the Speakers:

Carla Taylor, PhD is a Professor in the Department of Food and Human Nutritional Sciences at the University of Manitoba. She obtained her PhD at the University of Guelph and completed post-doctoral fellowships at the University of Michigan, Ann Arbor, and the University of Washington, Seattle. Her laboratory is located at the St. Boniface Albrechtsen Research Centre and she was Director of the Canadian Centre for Agri-food Research in Health and Medicine from 2015-2022. She holds funding from both NSERC and CIHR. Earlier in her career, she received the International Life Sciences Institute Future Leader Award in Nutrition, and the Canadian Society of Nutritional Sciences - Centrum Foundation New Scientist Award. She is currently a Senior Associate Editor for Lipids.Dr. Taylor's research program investigates how dietary components, such as lipids, protein, and bioactive compounds present in oilseeds and pulses, may be beneficial for prevention and management of obesity, type 2 diabetes and cardiovascular disease. The research approach employs dietary interventions in animal models of disease to investigate mechanisms, and clinical studies to apply the findings to humans. Dr. Taylor provides the nutritional sciences expertise in multi-disciplinary projects.

Mandana Pahlavani, Ph.D. is an Assistant Professor of Nutrition at Texas Woman's University in Denton, Texas. She has a strong research background in areas of Nutrition, Obesity, Cardiometabolic health, and Inflammation. Her doctoral research focused on determining mechanisms by which omega 3 fatty acids (n-3) polyunsaturated fatty acids, primarily eicosapentaenoic acid (EPA), activate brown adipose tissue and induce the thermogenic marker, uncoupling protein-1 (UCP-1) to reduce obesity. She was awarded a United States Department of Agriculture (USDA) Postdoctoral Fellowship to investigate gene and miRNA analyses of mechanisms mediating anti-inflammatory effects of fish oil and dose-dependent effects of fish oil in obesity. Her second postdoc at UT Southwestern Medical Center (UTSW), supported by the NIH T32 training program focuses on patient-oriented research in cardiometabolic health. She was awarded American Heart Association (AHA) Postdoctoral Fellowship to perform deep phenotyping approaches to understand the role of lipid metabolism in cardiometabolic health. Her current research investigates the link between extreme cholesterol efflux capacity (CEC), anti-inflammatory, and antioxidant functions of HDL in a diverse cohort of Dallas Heart Study. In addition, she will investigate the use of bioactive food compounds and nutrients such as polyphenols, antioxidants, and functional foods in reducing cardiovascular disease (CVD), obesity, and inflammation.

Original Source: "CNS Education Webinars" Friday, April 14, 2023.

The views expressed by speakers or other third parties in CNS webinars, events and/or conferences are those of the speaker or third-party and not necessarily of CNS.

Length: 1:06:19

Type: File

Last Updated: April 15, 2023

Name Type
Pahlavani - Metabolic Effects of Dietary Omega-3 Fatty Acids on Energy Homeostasis and Obesity File
Taylor - Dietary omega-3 fatty acidsfor healthy adipose tissue andreduction of cardiometabolic disease File
Recent insights into omega-3 fatty acid regulation of adipose tissue metabolism Video
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