Assessing risk of bias in nutrition studies 


NUQUEST Description:

Dietary exposure assessments are a critical issue in evaluating human nutrition studies; however, existing bias assessment tools do not consistently include nutrition-specific criteria. Here we report on the development of the Nutrition QUality Evaluation Strengthening Tools (NUQUEST) for randomized controlled trials, cohort studies and case-control studies. NUQUEST integrates nutrition-specific criteria with generic criteria from existing tools with demonstrated reliability and validity. Tools were developed using a comprehensive, 8-step process. Evaluations using a sample of nutrition studies produced high interrater reliability and concurrent validity as well as a user-friendly approach. Detailed guidance is presented to support users and the accompanying worksheet provides an optional framework to guide users through their ratings. NUQUEST represents a consistent and transparent approach for evaluating risk of bias issues related to dietary exposure assessment commonly encountered in human nutrition studies.

Objectives of the virtual workshop series: 

By attending this virtual workshop series, participants will: 

  1. Understand different types of epidemiological study designs used in nutrition research (randomized controlled trials, cohort studies and case-control studies) 
  2. Understand in detail how risk of bias can arise in nutrition studies
  3. Identify relevant text to inform risk of bias ratings for nutrition studies
  4. Know the key features of the NUQUEST (NUtrition QUality Evaluation Strengthening Tools) worksheets, checklists and guidance and when and how to apply
  5. Gain hands-on experience applying the NUQUEST worksheets, checklists, and guidance for assessing risk of bias in nutrition studies
  6. Produce and interpret overall risk of bias ratings for exemplar nutrition studies using NUQUEST

NUQUEST Working Group: Shannon Kelly, Amanda MacFarlane, George Wells, Linda Greene-Finestone, Stephen Brooks, Karima Benkhedda. Speaker bios can be viewed HERE

Virtual Workshop Series

  1. October 26, 2022, 1:00 - 4:00pm ET: Introduction to epidemiologic study designs and risk of bias concepts
  2. November 2, 2022, 1:00 - 4:00pm ET:  Introduction to NUQUEST
  3. November 9, 2022, 1:00 - 4:00pm ET: Application of NUQUEST


Workshop fees:

All fees are in Canadian dollars.  Pricing is based on CNS membership category. NOTE: Registration fee includes all 3 workshop sessions; register once for admittance to the full series.    

Register for workshop series

Session 1: October 26, 2022

Introduction to epidemiologic study designs and risk of bias concepts

Session 1: of the three-part workshop is optional. It is designed for individuals who need a formal presentation on the design and analysis of epidemiological studies. This will provide a basis for how bias can arise in these studies, which will be explored in greater detail in subsequent workshop sessions. 

View Session 1 Agenda  


Session 2: November 2, 2022

Introduction to NUQUEST

Session 2: Building on attendees’ knowledge of study design, analysis, and general risk of bias, in this second session we will look at nutrition-specific biases and introduce the key features of the NUQUEST checklists that can be used to evaluate bias in nutrition studies. Exemplars will be reviewed in an interactive manner alongside worked examples to highlight the process of assessing risk of bias.

View Session 2 Agenda 

Session 3: November 9, 2022

Application of NUQUEST

Session 3:  In this third and final session, participants will gain practical hands-on experience applying the NUQUEST tools in assessing the risk of bias. Breakout groups will present their assessment of one of the study designs and share their experiences using NUQUEST.

View Session 3 Agenda 

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